Immune System News

April 25, 2024

Top Headlines

Tumor Cells Evade the Immune System Early On: Newly Discovered Mechanism Could Significantly Improve Cancer Immunotherapies

Apr. 24, 2024 — Tumors actively prevent the formation of immune responses by so-called cytotoxic T cells, which are essential in combating cancer. Researchers have now uncovered for the first time how this exactly ...

Signs of Multiple Sclerosis Show Up in Blood Years Before Symptoms

Apr. 19, 2024 — In a discovery that could hasten treatment for patients with multiple sclerosis (MS), scientists have discovered a harbinger in the blood of some people who later went on to develop the ...

Vaccine Breakthrough Means No More Chasing Strains

Apr. 15, 2024 — Scientists at UC Riverside have demonstrated a new, RNA-based vaccine strategy that is effective against any strain of a virus and can be used safely even by babies or the ...

How the Body Switches out of 'Fight' Mode

Apr. 10, 2024 — Cortisone and other related glucocorticoids are extremely effective at curbing excessive immune reactions. But previously, astonishingly little was known about how they exactly do that. Researchers have now explored the molecular mechanism of action ...

Latest Headlines

updated 10:46pm EDT

Apply Single-Cell Analysis to Reveal Mechanisms of a Common Complication of Crohn's Disease

Apr. 24, 2024 — Study identifies key pathways underlying perianal fistula, a disease complication that is more prevalent and severe in African American ...

The Enemy Within: How Pathogens Spread Unrecognized in the Body

Apr. 22, 2024 — Some pathogens hide inside human cells to enhance their survival. Researchers have uncovered a unique tactic certain bacteria use to spread in the body without being detected by the immune system. In ...

Genetically Engineering a Treatment for Incurable Brain Tumors

Apr. 22, 2024 — Scientists are developing and validating a patent-pending novel immunotherapy to be used against glioblastoma brain tumors. Glioblastomas are almost always lethal with a median survival time of 14 ...

Metabolic Health Before Vaccination Determines Effectiveness of Anti-Flu Response

Apr. 18, 2024 — The annual influenza vaccine has become less effective on average over time. One reason may be reduced vaccine efficacy in people with obesity than ...

Study Opens New Avenue for Immunotherapy Drug Development

Apr. 19, 2024 — Researchers have designed a new method for developing immunotherapy drugs using engineered peptides to elicit a natural immune response inside the ...

Siblings With Unique Genetic Change Help Scientists Progress Drug Search for Type 1 Diabetes

Apr. 18, 2024 — Two siblings who have the only known mutations in a key gene anywhere in the world have helped scientists gain new insights that could help progress ...

Scientists Identify Pro-Aging 'Sugar Signature' in the Blood of People Living With HIV

Apr. 10, 2024 — Scientists have identified sugar abnormalities in the blood that may promote biological aging and inflammation in people living with ...

New Drug Prevents Flu-Related Inflammation and Lung Damage

Apr. 10, 2024 — Findings show a newly created drug can prevent runaway inflammation while still allowing the immune system to handle the virus, even when given late into ...

Researchers Identify Protein That Controls CAR T Cell Longevity

Apr. 10, 2024 — CAR T cell therapy has revolutionized the way certain types of cancer are treated, and the longer those CAR T cells live in a patient's body, the more effectively they respond to cancer. Now, ...

Respiratory Allergies: Newly Discovered Molecule Plays a Major Role in Triggering Inflammation

Apr. 10, 2024 — One of the molecules responsible for triggering the inflammation that causes allergic respiratory diseases, such as asthma and allergic rhinitis, has ...

Researchers Develop a New Way to Safely Boost Immune Cells to Fight Cancer

Apr. 19, 2024 — Researchers explore a cancer immunotherapy treatment that involves activating the immune cells in the body and reprogramming them to attack and destroy cancer cells. This therapeutic method ...

New Insights Could Unlock Immunotherapy for Rare, Deadly Eye Cancer

Apr. 16, 2024 — New research explains why metastatic uveal melanoma is resistant to conventional immunotherapies and how adoptive therapy, which involves growing a patient's T cells outside the body before ...

Treatment With Anti-Inflammatory Proteins Following Heart Attack Shows Promise to Reduce the Risk of Further Heart Damage

Apr. 4, 2024 — Research into the protective effects of two anti-inflammatory molecules, transforming growth factor-beta1 (TGF 1) and Heligmosomoides polygyrus TGM (HpTGM), following heart attack found that both ...

New Research Offers Insight Into the Future Understanding of MS and Its Treatments

Apr. 4, 2024 — Researchers have developed a new and unique blood test to measure the immune response to the Epstein Barr Virus (EBV) which is the leading risk factor for developing multiple sclerosis (MS). Their ...

Mitochondrial Roles in Antiviral Immunity Modify Manifestations of Neurological Diseases

Apr. 4, 2024 — Scientists report that a progressive neurodegenerative disease can be triggered by a viral infection. The mechanism relates to mitochondrial roles in antiviral defense ...

Discovery Into How Chronic Lung Conditions Affect Children's Immune System

Apr. 4, 2024 — Researchers have made a breakthrough into how two chronic respiratory diseases in childhood affect the immune system, paving the way for better ...

Immunotherapy for Alzheimer's Disease Shows Promise in Mouse Study

Apr. 3, 2024 — Scientists have shown that treating mice with an antibody that blocks the interaction between APOE proteins (white) sprinkled within Alzheimer's disease plaques and the LILRB4 receptor on ...

Hope for Treating Autoimmune Diseases

Apr. 3, 2024 — A routine blood test that measures a patient's inflammation levels could improve the early diagnosis and management of a wide range of debilitating autoimmune diseases. The Systemic Inflammation ...

Investigators Develop Novel Treatment for T-Cell Leukemias and Lymphomas

Apr. 2, 2024 — A novel treatment for leukemias and lymphomas that arise from immune system T cells was found to be effective at killing these cancers in mice bearing human T-cell ...

Gene Analysis Generates Spatial Map of Intestinal Cells and Traces Their Trajectories During Gut Inflammation

Apr. 2, 2024 — Cells within the intestines perform various roles including nutrient absorption, sensing, and maintaining homeostasis. Certain chronic disorders are distinctly characterized by gut inflammation, ...

Scientists Pioneer Immunotherapy Technique for Autoimmune Diseases

Apr. 1, 2024 — Scientists have developed an immunotherapy strategy that potentially lays the groundwork for treating a spectrum of autoimmune ...

'Exhausted' Immune Cells in Healthy Women Could Be Target for Breast Cancer Prevention

Mar. 28, 2024 — People carrying BRCA1 and BRCA2 gene mutations are at high risk of developing breast and ovarian cancer. Researchers have found that changes occur in the immune cells of breast tissue in carriers of ...

A Combination of Approved Drugs Enhances the Delivery of Anti-Bacterial Medications to Treat Tuberculosis

Mar. 27, 2024 — Researchers have found that approved drugs that were originally shown to normalize blood vessels surrounding tumors (to improve drug delivery to cancer cells) can enhance the delivery of ...

Making Long-Term Memories Requires Nerve-Cell Damage

Mar. 27, 2024 — Just as you can't make an omelet without breaking eggs, scientists have found that you can't make long-term memories without DNA damage and brain ...

Researchers Create Biocompatible Nanoparticles to Enhance Systemic Delivery of Cancer Immunotherapy

Mar. 27, 2024 — Researchers are enhancing immunotherapy effects against malignant tumors by developing and validating patent-ending poly (lactic-co-glycolic acid), or PLGA, nanoparticles modified with adenosine ...

Old Immune Systems Revitalized in Mouse Study, Improving Vaccine Response

Mar. 27, 2024 — Those with aging immune systems struggle to fight off novel viruses and respond weakly to vaccination. Researchers were able to revitalize the immune system in ...

Researchers a Step Closer to a Cure for HIV

Mar. 26, 2024 — A new study shows virus-like particle can effectively 'shock and kill' latent HIV reservoir in those living with chronic ...

Genetically Engineered Dendritic Cells Enhance the Power of Immunotherapy Against Lung Cancer

Mar. 26, 2024 — A new study suggest that using CXCL9 and CXCL10-producing dendritic cells alongside immunotherapy can be a promising strategy to overcome treatment resistance and improve clinical outcomes for ...

Gene Discovery Offers New Hope for People Living With Chronic Skin Disease

Mar. 25, 2024 — Scientists have discovered a gene mutation is responsible for causing psoriasis -- a chronic inflammatory skin disease that causes patients to develop red, scaly and itchy patches across their body. ...

An Immunotherapy to Overcome Resistant Leukemia

Mar. 21, 2024 — Researchers have discovered that a specific mutation in the cancer cells of an aggressive type of blood cancer can prevent novel immunotherapies such as CAR T-cell therapy from working. Their study ...