Brain Tumor News

April 19, 2024

Top Headlines

Zika Virus Vaccine Emerges as an Unlikely Hero in Battling Brain Cancer

Mar. 8, 2024 — Scientists have developed a new approach using the Zika virus to destroy brain cancer cells and inhibit tumor growth, while sparing healthy ...

Foundation Laid for Improved Diagnostic Imaging of Brain Tumors

Jan. 3, 2024 — Research team draws up criteria for PET-based examinations of malignant brain ...

Understudied Cell in the Brain Could Be Key to Treating Glioblastoma

Dec. 12, 2023 — Glioblastoma is one of the most treatment-resistant cancers, with those diagnosed surviving for less than two years. In a new study, researchers have found that a largely understudied cell could offer new insight into how the aggressive, primary ...

Researchers Identify Cell Signaling Pathway Controlling Melanoma Cell Metastasis to the Brain

Nov. 29, 2023 — Researchers have been working to better understand what drives melanoma brain metastasis. They now report on the identification of a cell signaling pathway that regulates the metastatic spread of ...

Latest Headlines

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'Dual-Target' Cell Therapy Appears to Shrink Brain Tumors, Research Finds

Mar. 13, 2024 — Targeting two brain tumor-associated proteins -- rather than one -- with CAR T cell therapy shows promise as a strategy for reducing solid tumor growth in patients with recurrent glioblastoma (GBM), ...

New Model of Key Brain Tumor Feature Could Help Scientists Understand How to Develop New Treatments

Feb. 29, 2024 — Researchers are exploiting a unique biological feature of glioblastoma to gain a better understanding of how this puzzling brain cancer develops and ...

New Study Offers Hope for Thousands Impacted Each Year by Aggressive Brain Cancer

Feb. 15, 2024 — New research identifies protein (PANK4) as an obstacle that blocks cancer cells from responding to chemotherapeutic treatment for ...

Cancer GPS Method Evaluates Model Tumor Malignancy

Jan. 22, 2024 — A water-soluble, luminescent europium complex enables evaluation of malignancy grade in model glioma tumor ...

Reprogrammed Fat Cells Support Tumor Growth

Jan. 3, 2024 — Mutations of the tumor suppressor p53 not only have a growth-promoting effect on the cancer cells themselves, but also influence the cells in the tumor's microenvironment. Scientists have now shown ...

Drugs Already Licensed Could Be Trialled to Potentially Treat Secondary Brain Cancer

Nov. 29, 2023 — The largest review of papers for brain cancer that has spread from the lungs has found abnormalities in the brain cancer and for which licensed drugs ...

CRISPR-Powered 'Cancer Shredding' Technique Opens New Possibility for Treating Most Common and Deadly Brain Cancer

Nov. 27, 2023 — The gene-editing technology CRISPR shows early promise as a therapeutic strategy for the aggressive and difficult-to-treat brain cancer known as ...

Promising Target for CAR T Cells Helps Cancer Trick the Immune System

Nov. 21, 2023 — GRP78 is a promising CAR T-cell immunotherapy target for brain and solid tumors. Discover why it's special, including how cancer uses it to trick immune ...

Cancer Stem Cells Trigger Macrophage Aging

Nov. 14, 2023 — Cancer stem cells cause the aging of macrophages in mice with healthy immune systems, creating conditions for the formation of ...

DNA Organization Influences the Growth of Deadly Brain Tumors in Response to Neuronal Signals

Oct. 31, 2023 — A pioneering study has unveiled that the 3D organization of DNA can influence the progression of the aggressive brain tumor known as glioblastoma. ...

New Clue to Treat Brain Cancer

Oct. 27, 2023 — A new research study shows that cerebrospinal fluid reduces current treatment efficacy in brain cancer and identifies new therapeutic opportunities. Cerebrospinal fluid, the clear colourless liquid ...

Mitochondrial Protein Plays Key Role in Glioblastoma and Therapeutic Resistance

Oct. 17, 2023 — Glioblastoma is the most common type of brain tumor that affects adults and, unfortunately, still remains incurable. In a new study, researchers have demonstrated that a specific mitochondrial ...

Brain Tumor Treatment by Targeting TUG1, a Gene That Controls Replication Stress

Oct. 12, 2023 — A new study has revealed a crucial link between the TUG1 gene and the ability of cancer cells to proliferate under high-stress conditions. Targeting this gene with a new therapy suppressed tumor ...

Avatars to Help Tailor Glioblastoma Therapies

Oct. 4, 2023 — Scientists have created a new zebrafish xenograft platform to screen for novel treatments for an aggressive brain tumor called glioblastoma, according to a new ...

Study Shows How Brain Tumors Make Certain Immune Cells Turn Traitor

Sep. 28, 2023 — A new study has for the first time exhaustively analyzed neutrophils that reside in brain tumors, detailing how the immune cells support brain cancer survival and how they're manipulated by the ...

Mutation-Specific Peptide Vaccine Against Midline Gliomas Used in Patients

Sep. 21, 2023 — Tumor vaccines can help the body fight cancer. These vaccines alert the patient's immune system to proteins that are carrying cancer-typical alterations. Physicians and cancer researchers have ...

New Research Signals a Quantum Leap for Brain Tumor Treatment

Sep. 14, 2023 — Researchers have discovered a new way to target and kill cancer cells in hard-to-treat brain tumours using electrically charged molecules to trigger self-destruction, that could be developed into a ...

Microdevices Implanted Into Tumors Offer New Way to Treat Brain Cancer

Sep. 6, 2023 — Researchers have designed a device that can help test treatments in patients with gliomas, a type of tumor that originates in the brain or spinal ...

Study Could Help Explain Why Certain Brain Tumors Don't Respond Well to Immunotherapy

Sep. 1, 2023 — A study sheds new light on why tumors that have spread to the brain from other parts of the body respond to immunotherapy while glioblastoma, an aggressive cancer that originates in the brain, does ...

Using the Body's 'Invisible Scalpel' to Remove Brain Cancer

Aug. 11, 2023 — Scientists discovered that anti-CTLA-4 immunotherapy extended the lives of mice with glioblastoma by causing specialized CD4+ T immune cells to 1) infiltrate the brain and 2) tell brain-resident ...

Efficient Boron Neutron Capture Therapy for Brain Tumor With Novel Boron Carrier

July 13, 2023 — A new boron agent drastically improves the effectiveness of boron neutron capture therapy for glioblastoma. The agent is selectively absorbed by brain tumor cells, exhibits enhanced blood retention, ...

AI Tool Decodes Brain Cancer's Genome During Surgery

July 7, 2023 — New AI tool enables in-surgery genomic profiling of gliomas, the most aggressive and most common brain tumors. This information offers critical clues about how aggressive a cancer is, its future ...

Vaccine Delivers a Boost to T Cell Therapy

July 5, 2023 — A new vaccine boosts the response of engineered CAR-T cells and helps the immune system generate T cells that target other tumor antigens. The researchers found this approach made it more likely that ...

Urine Tests Identify Brain Tumors by Capturing Cancer DNA Using Nanowires

July 3, 2023 — A group led by researchers at Nagoya University in Japan used nanowires to develop a technology for capturing cell-free DNA from cancer cells in urine samples. Using their technique, they captured ...

New Discovery Can Help Detect Brain Tumors

June 15, 2023 — Folate-based radiopharmaceuticals can be used in positron emission tomography (PET) imaging to detect folate receptors in brain tumours. The discovery of folate receptors and their exploitation ...

Biodegradable Ultrasound Opens the Blood-Brain Barrier

June 14, 2023 — A new, biodegradable ultrasound far more powerful than previous devices could make brain cancers more treatable, researchers ...

Breakthrough in Glioblastoma Treatment With the Help of a Virus

June 12, 2023 — Researchers are describing the results of a recent clinical trial -- a breakthrough in glioblastoma treatment with the help of a modified cold virus injected directly into the tumor. When combined ...

New Drug Delays Progression of Glioma, a Deadly Brain Cancer

June 5, 2023 — Scientists have shown that a new targeted therapy drug can extend the amount of time people with a subtype of glioma are on treatment without their cancer worsening. The finding suggests a possible ...

Open-Analysis Platform for Pediatric Brain Tumors Provides Robust Data Resource for Childhood Cancer Research

May 31, 2023 — Researchers have partnered to create a first-of-its-kind open-source, reproducible analysis platform for pediatric brain tumors. With the help of thousands of genomically sequenced samples, ...

Scientists Discover a Deadly Brain Cancer's Hidden Weakness

May 12, 2023 — The difficult-to-treat brain cancer glioblastoma steals a person's mental faculties as it spreads, yet the tumor's insidious ability to infiltrate neighboring networks in the brain could ...